Autologous Nasal Chondrocytes and a Cellulose-Based Self-Setting Hydrogel for the Repair of Articular Cartilage in Horses
نویسندگان
چکیده
Galway, Ireland Autologous Nasal Chondrocytes and a Cellulose-Based Self-Setting Hydrogel for the Repair of Articular Cartilage in Horses C. Vinatier; O. Geffroy; C. Merceron; O. Gauthier; B. H. Fellah; S. Portron; M. Masson; J. Lesoeur; P. Weiss; J. Guicheux 1,3 Corresponding Author: [email protected] 1 Inserm U 791, LIOAD, group “STEP” (skeletal tissue engineering and physiopathology), Nantes, France. 2 GRAFTYS SA, Aix en Provence Nantes, France. 3 National Veterinary School, Experimental Surgery Department, Nantes, France
منابع مشابه
Study of Human Chondrocyte Redifferntiation Capacity in Three-Dimensional Hydrogel Culture
Objective(s) Articular cartilage tissue defects cannot be repaired by the proliferation of resident chondrocytes. Autologous chondrocyte transplantation (ACT) is a relatively new therapeutic approach to cover full thickness articular cartilage defects by in vitro grown chondrocytes from the joint of a patient. Therefore, we investigated the redifferentiation capability of human chondrocytes ma...
متن کامل3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation.
Human articular cartilage is highly susceptible to damage and has limited self-repair and regeneration potential. Cell-based strategies to engineer cartilage tissue offer a promising solution to repair articular cartilage. To select the optimal cell source for tissue repair, it is important to develop an appropriate culture platform to systematically examine the biological and biomechanical dif...
متن کاملConditioned medium derived from mesenchymal Stem cells regenerates’ defected articular cartilage
Background & Aims: One of cell- based technical issues associated with cartilage repair assay is delivering cells to the site of the parts where damage is created. Mesenchymal stem cells (MSCs) with their chondrogenic potential are ideal candidates for cartilage regeneration. High expression of cartilage hypertrophy markers by MSCs would result in apoptosis and ossification. This investigation ...
متن کاملCostal Versus Articular Chondrocytes in Alginate Three-Dimensional Cultures
Given the difficulties in accessing articular cartilage as a source of chondrocytes to be used in fabricating cartilage constructs, alternative sources are required. The present study examined chondrocytes from costal cartilage for their suitability in cartilage tissue engineering. Chondrocytes isolated from rat knee and rib hyaline cartilage were separately mixed with alginate and placed in a ...
متن کاملSelf-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair.
Emerging medical technologies for effective and lasting repair of articular cartilage include delivery of cells or cell-seeded scaffolds to a defect site to initiate de novo tissue regeneration. Biocompatible scaffolds assist in providing a template for cell distribution and extracellular matrix (ECM) accumulation in a three-dimensional geometry. A major challenge in choosing an appropriate sca...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2010